Documenting Cloud Labs and Examining How Remotely Operated Automated Laboratories Could Enable Bad Actors

Ying-Chiang Jeffrey Lee, Bria Persaud, Barbara Del Castello, Allison Berke, Gustavs Zilgalvis

Expert InsightsPublished Apr 24, 2025

Research laboratories that allow for remote execution of experiments and rely heavily on automation, known as cloud labs, can be manifestations of the convergence of artificial intelligence and biotechnology. However, the automation and remote capabilities that define cloud labs also could introduce specific risks, particularly in the context of biosecurity. The potential for misuse by malicious actors to develop harmful chemical or biological weapons through these platforms is a notable concern.

In this paper, the authors provide an overview of 15 cloud lab organizations around the world, including details on the facility size, the number of scientific instruments, location, and the type of science they focus on. The authors then discuss how cloud labs could enable bad actors in developing and proliferating chemical or biological weapons. This discussion may be of interest to cloud lab organizations and stakeholders in science automation who have responsibilities to inform policymakers about the current state of cloud lab organizations and potential vulnerabilities of the cloud lab model to facilitate the safe and secure development of scientific cloud labs.

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Lee, Ying-Chiang Jeffrey, Bria Persaud, Barbara Del Castello, Allison Berke, and Gustavs Zilgalvis, Documenting Cloud Labs and Examining How Remotely Operated Automated Laboratories Could Enable Bad Actors, RAND Corporation, PE-A3851-1, April 2025. As of April 24, 2025: https://www.rand.org/pubs/perspectives/PEA3851-1.html

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Lee, Ying-Chiang Jeffrey, Bria Persaud, Barbara Del Castello, Allison Berke, and Gustavs Zilgalvis, Documenting Cloud Labs and Examining How Remotely Operated Automated Laboratories Could Enable Bad Actors. Santa Monica, CA: RAND Corporation, 2025. https://www.rand.org/pubs/perspectives/PEA3851-1.html.
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This work was conducted by the Technology and Security Policy Center within RAND Global and Emerging Risks.

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