Topic Brief: Infantile Epilepsy

The goal of the topic brief is to identify key management strategies for infantile epilepsy; provide an overview of clinical practice guidelines, systematic reviews, and randomized controlled trials that assess infantile epilepsy; and highlight evidence gaps.

An Evidence Map of Treatments for Infantile Epilepsy

We conducted a scoping review of interventions for management of epilepsy among infants and display our results in an evidence map.

Responsiveness of the Quality of Life in Epilepsy Inventory (QOLIE-89) in an Antiepileptic Drug Trial

Responsiveness of this HRQOL measure can be reported in terms of previously established benchmarks for ESs, which can be predicted from other indices.

Seizure Reduction and Quality of Life Improvements in People with Epilepsy

In this study, HRQOL improvement occurred primarily among patients who achieved complete seizure freedom.

Quality of Life Measures in Epilepsy: How Well Can They Detect Change Over Time?

Epilepsy-targeted health-related quality of life measures may be preferable to generic ones in longitudinal studies.

Outcomes in 248 patients who had diagnostic evaluations for epilepsy surgery

Outcomes in 248 patients who had diagnostic evaluations for epilepsy surgery

Agreement between self reports and proxy reports of quality of life in epilepsy patients

Agreement between self reports and proxy reports of quality of life in epilepsy patients

Development of the Quality of Life in Epilepsy Inventory

Describes the development of a 99-item epilepsy HRQOL inventory that includes the SF-36 as its core.

Reliability and Validity of the Katz Adjustment Scales in an Epilepsy Sample

Development of quality of life measures de novo is time-consuming and expensive, and a number of instruments are already available for general use.

Clinical Epilepsy Section, National Institute of Neurological Disorders and Stroke

Epilepsy Surgery Inventory 55 Survey (ESI-55)

The ESI-55 Epilepsy Surgery Inventory taps eleven health concepts: health perceptions; energy/fatigue; overall quality of life; social functioning; emotional well-being; cognitive functioning; role limitations due to emotional problems, memory problems, or physical health problems; physical functioning; and pain.

Quality of Life in Epilepsy Inventory (QOLIE-89 and QOLIE-31)

The QOLIE-89 contains 17 multi-item measures of overall quality of life, emotional well-being, role limitations due to emotional problems, social support, social isolation, energy/fatigue, worry about seizure, medication effects, health discouragement, work/driving/social function, attention/concentration, language, memory, physical function, pain, role limitations due to physical problems, and health perceptions. The QOLIE-31 is the short-form version of the original QOLIE-89 instrument.